This article is a timeline of inventions made by people who were citizens of the United States, or its predecessor colonies.

On March 6, 1646, the first patent in North America was issued to Joseph Jenckes by the General Court of Massachusetts for making scythes. On April 10, 1790, President George Washington signed a bill into law establishing the modern patent and trademark system which continues to be used to this day. As of February 10, 2009, the United States Patent and Trademark Office has granted 7,479,950 patents Examples of patents include Nikola Tesla’s transmission of radio, Ransom Eli Olds’ assembly line, and Willis Carrier’s air-conditioning.

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